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KMID : 0931320140140020121
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대한상부위장관.헬리코박터학회지
2014 Volume.14 No. 2 p.121 ~ p.125
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A Rare Case of Gastric Carcinosarcoma with Neuroendocrine Differenti
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Shin Hae-Jin
Ju Jong-Seok
Moon Hee-Seok
Kang Sun-Hyung
Sung Jae-Kyu
Jeong Hyun-Yong
Song Kyu-Sang
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Abstract
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Carcinosarcoma of the stomach is a rare biphasic tumor that consists of both carcinomatous and sarcomatous components. In the gastrointestinal tract, carcinosarcoma is most frequently seen in the esophagus and rarely in the stomach. Tubular or papillary ad-enocarcinomas are common carcinomatous components, whereas mesenchymal sarcomatous components may vary. Neuroendo-crine carcinomatous differentiation in carcinomatous components is extremely rare. We report a 62-year-old female patient with a history of dyspepsia for one-month-history. Endoscopic findings showed a ulcerofungating lesion, which infiltrated from the poste-rior wall of the antrum to the posterior wall of the gastric angle. Radical subtotal gastrectomy was performed. In the resected speci-men, immunohistochemical studies showed two positive reactions for epithelial and mesenchymal markers. Based on the above findings, the patient was diagnosed with a gastric carcinosarcoma with neuroendocrine differentiation.
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KEYWORD
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Carcinosarcoma, Stomach, Neuroendocrine differentiation factor, human, Immunohistochemistry
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